Rejuran Treatment- Skin Rejuvenation & Benefits Explained

What Is Rejuran?

Rejuran is an advanced injectable skin rejuvenation treatment that utilizes polynucleotides (PN), which are biocompatible and purified DNA fragments extracted from salmon sperm. These DNA fragments closely resemble human DNA and are renowned for their exceptional regenerative and anti-inflammatory properties. Rejuran was first introduced in South Korea and has since gained global traction due to its ability to stimulate tissue repair, strengthen skin elasticity, and restore the skin’s natural barrier.

This treatment falls under the category of skin boosters and is classified as a bioremodelling therapy, meaning it doesn’t just plump or mask imperfections like fillers, it actively repairs and revitalizes skin from a cellular level. By improving skin quality, tone, and texture over time, Rejuran is often referred to as the “baby skin injection” because of the youthful softness and radiance it helps restore.

How Does Rejuran Work?

The Rejuran process initiates a regenerative response at the cellular level, strengthening skin texture, elasticity, and healing. The secret lies in the biochemical composition and the skin’s ability to respond to nucleotides as building blocks for repair.

1. The Key Ingredient: Polynucleotides (PNs)

At the heart of Rejuran’s formulation is salmon-derived polynucleotide (PN) therapy, a highly purified DNA fragment extracted from the sperm of Oncorhynchus mykiss (a species of salmon). These PNs are biocompatible with human skin and are free from immunogenic reactions.

Quantity and Concentration:

Each 2 mL syringe of Rejuran Healer contains:

2 mg/mL of polynucleotide concentration
Total: 4 mg of PNs per syringe

This concentration has been clinically studied to stimulate fibroblast activity, enhance skin elasticity, and accelerate tissue regeneration.

2. Mechanism of Action: Cellular Repair & Anti-Inflammation

Once injected into the dermis, these polynucleotides initiate several beneficial processes:

Stimulate Fibroblast Proliferation:

PNs serve as natural bio-activators, encouraging the growth of fibroblasts, which are critical cells for producing collagen and elastin.

Promote Angiogenesis:

Polynucleotides have been shown to stimulate vascular endothelial growth factor (VEGF) expression, promoting the formation of new blood vessels for better oxygen and nutrient delivery.

Anti-inflammatory Action:

PNs also reduce levels of pro-inflammatory cytokines like TNF-alpha and IL-6. This helps calm inflamed or damaged skin and creates a more favorable environment for healing.

Antioxidant Protection:

They scavenge reactive oxygen species (ROS), reducing oxidative stress, one of the primary causes of skin aging.

3. Additional Components in the Formulation

Although polynucleotides are the hero ingredient, the full Rejuran formulation often includes:

Sodium chloride (NaCl) maintains isotonicity
Phosphate buffer stabilizes pH between 6.8 and 7.5
Water for injection serves as the carrier medium

These excipients ensure safe, stable, and effective delivery of the polynucleotides into the skin layers.

4. Skin Renewal Timeline

Within 1 Week: Inflammation begins to reduce, and minor hydration improvements are seen.
After 2–4 Weeks: Collagen synthesis ramps up; fine lines and pores begin to shrink.
After 6–8 Weeks: Skin looks firmer, smoother, and visibly more radiant due to improved dermal matrix density

5. Scientific Support

Several clinical trials have validated Rejuran’s efficacy:

A 2017 study published in the Journal of Cosmetic Dermatology showed a 22% improvement in skin elasticity and a 14% increase in dermal density after 4 sessions.
Histological studies have also shown increased collagen I and III expression in treated skin, validating its regenerative action at the microscopic level.

Types of Rejuran Treatment

Rejuran treatments have gained popularity for their ability to improve skin texture, reduce wrinkles, and enhance overall skin vitality. At the heart of these treatments lies polynucleotides (PNs), a cutting-edge ingredient derived from salmon DNA. Let’s explore the different types of Rejuran treatments and take a closer look at the chemicals used in each, as well as how their quantities and properties contribute to skin rejuvenation.

Rejuran Healer, PN Injection

Rejuran Healer is a rejuvenating treatment that uses the healing properties of polynucleotides (PNs), which are short chains of nucleotides, building blocks of DNA. This treatment is designed to restore skin health at a cellular level, promoting collagen production and accelerating the skin’s natural healing process.

Key Chemical Ingredient: Polynucleotides (PNs) – The main component of Rejuran Healer is polynucleotides, which are derived from salmon DNA. These molecules play a crucial role in enhancing skin repair, promoting collagen synthesis, and boosting hydration.

Concentration and Quantity: Typically, the concentration of polynucleotides in a Rejuran Healer treatment is around 1-2 mg per mL. The quantity injected during a treatment session can vary, but it usually ranges from 1 to 3 mL per session, depending on the area treated and the individual’s skin condition.

Mechanism of Action: Polynucleotides in Rejuran Healer promote fibroblast activity, which is essential for the production of collagen and elastin. This not only improves the elasticity of the skin but also enhances its ability to repair and regenerate.

Rejuran I, Eye Area Treatment

The Rejuran I treatment is specifically formulated for the delicate skin around the eyes. This treatment targets fine lines, dark circles, and skin laxity, rejuvenating the skin with the healing power of polynucleotides.

Key Chemical Ingredient: Polynucleotides (PNs) – As with the original Rejuran Healer treatment, Rejuran I contains the same polynucleotide compound. However, the formulation is more refined to cater to the sensitive skin around the eyes.

Concentration and Quantity: The concentration of polynucleotides in Rejuran I is generally the same as in the Healer treatment, at 1-2 mg per mL. The quantity used per session is typically 0.5 to 1 mL due to the targeted application around the eye area.

Mechanism of Action: The high concentration of polynucleotides stimulates collagen production and improves blood circulation in the under-eye area. This helps to reduce puffiness and dark circles, providing a youthful, refreshed appearance.

Rejuran S, Skin Tightening

Rejuran S is designed for patients seeking more significant skin rejuvenation, particularly in areas with loose or sagging skin. It focuses on improving skin elasticity and stimulating the production of collagen and elastin fibers.

Key Chemical Ingredient: Polynucleotides (PNs) combined with additional growth factors may be included in this formulation to enhance the rejuvenating effects on the skin.

Concentration and Quantity: The concentration of polynucleotides is similar to Rejuran Healer, typically 1-2 mg per mL, though the overall treatment may involve larger quantities of injection depending on the treatment area. Typically, 1 to 3 mL of Rejuran S is injected per session.

Mechanism of Action: By delivering higher concentrations of polynucleotides, Rejuran S accelerates collagen synthesis and stimulates fibroblast activity more aggressively, leading to tighter and more youthful-looking skin.

Rejuran Plus, Skin Resurfacing

Rejuran Plus is a specialized version of Rejuran used for resurfacing and smoothing rough or textured skin. This treatment is often chosen for those with acne scars or uneven skin tone.

Key Chemical Ingredient: Polynucleotides (PNs), combined with growth factors and hyaluronic acid, make Rejuran Plus particularly effective for resurfacing the skin and boosting hydration.

Concentration and Quantity: The concentration of polynucleotides in Rejuran Plus is around 1-2 mg per mL, with hyaluronic acid at about 1-2 mg per mL. The quantity used in a session is similar to other Rejuran treatments, with typically 1 to 2 mL per session.

Mechanism of Action: The combination of polynucleotides and hyaluronic acid helps to plump and hydrate the skin, smoothing out fine lines and improving skin texture. The growth factors present also encourage faster healing of skin imperfections, such as scars or uneven pigmentation.

Benefits of Rejuran Treatment in Detail

Rejuran, a revolutionary skin treatment, continues transforming aesthetic medicine, offering profound benefits for skin rejuvenation. At its core, Rejuran leverages polynucleotide therapy, where the main active component is salmon DNA that closely mirrors human DNA in structure and function. This precision makes Rejuran incredibly effective in repairing skin and maintaining its integrity. Below are more in-depth details of its mechanisms and effects.

1. Deep Cellular Regeneration and Repair

The primary action of Rejuran is to regenerate skin at the cellular level. The active polynucleotides (PN) found in Rejuran promote the repair of damaged tissues by encouraging cellular turnover. These nucleotides are the building blocks of DNA and RNA, which play a central role in cellular function and division. When injected into the skin, the polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and elastin, to increase their activity. This promotes skin rejuvenation from within, helping to reverse damage caused by aging, UV exposure, and environmental stressors.

2. Strengthen Collagen Production

Collagen is essential for maintaining skin’s firmness, elasticity, and youthful appearance. As we age, the body’s natural collagen production decreases, leading to sagging skin, wrinkles, and fine lines. Rejuran’s polynucleotides stimulate collagen type I and III synthesis, which are the most abundant collagen types in the dermis and are responsible for the skin’s strength and elasticity.

Quantitative Impact on Collagen: Studies have shown that after a series of Rejuran treatments, collagen synthesis can increase by up to 30% over weeks. This improves skin structure, smoothing out wrinkles, and restoring skin tone and texture. This process not only addresses existing wrinkles but also prevents the formation of new fine lines by enhancing the skin’s structural integrity.

3. Restoration of Skin Hydration through Hyaluronic Acid Stimulation

One of Rejuran’s remarkable effects is its ability to enhance skin hydration. The polynucleotides stimulate the synthesis of hyaluronic acid within the skin. Hyaluronic acid is a naturally occurring substance that retains moisture, and it is known for its ability to hold 1000 times its weight in water. By increasing the production of hyaluronic acid, Rejuran helps to attract and retain moisture, ensuring the skin remains plump, hydrated, and smooth.

4. Reduction in Inflammation and Skin Sensitivity

The anti-inflammatory effects of Rejuran are particularly beneficial for individuals with acne, rosacea, and other inflammatory skin conditions. Polynucleotides possess anti-inflammatory properties that help reduce redness and irritation by modulating the immune response in the skin. This is crucial because chronic inflammation can exacerbate conditions like acne and rosacea and lead to further skin damage over time. By reducing inflammation, Rejuran helps improve overall skin health and prevents long-term skin irritation and scarring.

Scientific Mechanism: Polynucleotides are able to interact with the immune cells in the dermis, specifically macrophages and dendritic cells, to regulate inflammatory pathways. This leads to reduced cytokine production, a critical mediator in inflammation, thus soothing the skin and accelerating the healing process.

5. Improved Skin Texture, Elasticity, and Skin Tone

As mentioned, Rejuran improves skin texture and tone, but its effects are also seen in its ability to restore skin elasticity. Promoting collagen and elastin production helps skin bounce back and tighten. The result is a firmer, smoother skin surface that looks naturally rejuvenated without looking overfilled, as sometimes happens with other aesthetic treatments.

For those struggling with skin discoloration or uneven pigmentation, Rejuran also works to lighten hyperpigmentation, including sun spots, age spots, and post-acne scars, by promoting the shedding of old skin cells and regenerating the skin with fresh, healthy cells.

6. Scientific Insight into the Chemical Composition of Rejuran

The polynucleotides used in Rejuran are derived from salmon sperm DNA, which contains specific sequences that help repair human skin cells. Salmon DNA is rich in purine and pyrimidine bases, key components of DNA that help in cellular division and repair. The high similarity between salmon and human DNA means the treatment is highly biocompatible and effective in human skin repair processes.

In Rejuran, these polynucleotides are isolated, purified, and fragmented into smaller pieces, allowing them to penetrate the dermis more effectively. Once in the dermis, these fragments interact with skin fibroblasts and other dermal cells to encourage collagen production, reduce inflammation, and accelerate tissue repair.

The typical concentration of polynucleotides in Rejuran is 1.5 to 2 mg per ml of treatment solution. This concentration has been shown to be optimal for stimulating the regenerative properties of the skin without causing adverse effects, ensuring both efficacy and safety.

Key chemical compounds include:

Purines, adenine and guanine: Vital for DNA synthesis, promoting skin cell repair and regeneration.
Pyrimidines (cytosine and thymine): Essential for the stability of DNA, contributing to cellular growth and skin elasticity.

7. Anti-Aging Effects Beyond Surface Treatment

In addition to its visible effects on wrinkles and skin texture, Rejuran goes deeper, working at the subcutaneous level. As the polynucleotides stimulate deeper skin layers, they also help to restore fat tissue that may have been lost due to aging. This helps fill in hollow areas, giving the face a more youthful contour without the need for invasive procedures.

8. Clinical Results and Long-Term Benefits

Clinical studies have demonstrated that Rejuran’s benefits extend beyond improving the skin’s appearance. With repeated treatments, patients experience long-term skin rejuvenation. The full effects are usually seen after 3 to 5 sessions, with maintenance treatments every 6 to 12 months for ongoing skin health.

In one study conducted in South Korea, researchers reported visible improvement in their skin texture, tone, and elasticity after three treatments of Rejuran, with results lasting for up to 6 months.

How Much Is Rejuran Treatment?

The cost of Rejuran treatment can vary significantly depending on several factors, including the location of the treatment center, the expertise of the healthcare professional, the number of sessions required, and the specific type of Rejuran treatment you’re receiving. Rejuran is a highly effective skin treatment that uses polynucleotide (PN) to rejuvenate and repair damaged skin, which can help address concerns like fine lines, wrinkles, skin elasticity, acne scars, and more. Here’s a breakdown of the costs and factors that can influence the price of this treatment:

Average Cost of Rejuran Treatment

On average, Rejuran treatment typically costs between $500 and $1,500 per session. However, prices can vary based on the specific clinic or dermatologist providing the treatment. For example:

Single Session: A single Rejuran session generally costs between $500 and $800. The exact cost depends on the region, as clinics in metropolitan areas may charge more due to higher overhead costs.

Package Deals: Many clinics offer package deals, which can significantly reduce the cost per session. For instance, purchasing a package of 3-5 sessions could reduce the per-treatment cost by 10-20%. The total cost for a Rejuran package may range from $1,500 to $4,000.

Factors That Affect the Price of Rejuran Treatment

Location: The geographic location of the clinic plays a significant role in pricing. Clinics in large cities or luxury areas might charge a premium for their services. For example, clinics in cities like New York, Los Angeles, or Singapore are likely to have higher costs compared to smaller towns or less-populated regions.
Clinic Reputation and Expertise: Experienced dermatologists or licensed medical professionals with a strong reputation in aesthetic treatments may charge more due to their level of expertise and the quality of care they provide.
Type of Rejuran Treatment: There are different types of Rejuran treatments, such as Rejuran Healer (which targets skin rejuvenation) and Rejuran I (for improving acne scars). The specific treatment used, along with the volume of product injected, can influence the overall cost. Rejuran I, for example, may require a more intensive application of the product to target deeper skin issues, thus raising the price.
Additional Procedures: Many individuals combine Rejuran treatment with other skincare procedures, such as Botox, dermal fillers, or laser treatments. If you opt for a combination package, the cost can be higher. For example, you may pay an additional $300-$500 if you combine Rejuran with laser resurfacing treatments for more comprehensive skin rejuvenation.

How Many Sessions Do You Need?

The number of sessions required will also affect the total cost. Rejuran is often recommended in a series of treatments to achieve optimal results:

For Skin Rejuvenation: Typically, patients undergo 2-3 sessions spaced 2-4 weeks apart for the best results. In some cases, a maintenance session might be recommended every 6 months, which would add to the overall cost.
For Acne Scarring: For more severe acne scars, a patient may need more sessions—anywhere from 4 to 6 sessions spaced several weeks apart. This could result in a treatment cost totaling up to $4,000 or more.
For Anti-Aging: Patients using Rejuran for anti-aging purposes may opt for 1-2 treatments per year after an initial series of 2-3 sessions. This can help maintain the effects of the treatment over the long term.

What Does the Cost Cover?

The cost of Rejuran treatment typically includes:

Consultation Fees: Many clinics include the consultation in the overall price, but some may charge separately for an initial consultation. Expect to pay anywhere from $50 to $200 for this consultation, depending on the clinic.
Treatment Costs: The price of the treatment itself covers the Rejuran product and the professional application. The cost may also include aftercare products or advice for managing the skin post-treatment.
Follow-Up Care: Some clinics provide follow-up consultations or check-ins to ensure the treatment is working as expected, and these may be included in the cost or charged separately.

Is Rejuran Treatment Worth the Cost?

While Rejuran treatment may seem expensive, it is considered a highly effective and non-invasive option for skin rejuvenation. The benefits of Rejuran, such as improved skin texture, reduced wrinkles, and smoother, younger-looking skin, can be seen within just a few weeks after the initial treatment. Furthermore, the results tend to last longer than other non-invasive skin treatments, which can make it a cost-effective solution in the long term.

Patients often report a noticeable improvement in their skin’s appearance and health after completing a series of treatments. This long-lasting improvement, combined with minimal downtime and discomfort, can make Rejuran a worthwhile investment for those looking to enhance their skin without undergoing surgery.

What Are the Side Effects of Rejuran Treatment?

Rejuran is widely known for its positive effects, including enhanced skin elasticity, reduced fine lines, and a more radiant complexion. It is essential to consider the potential side effects that may arise from this treatment.

Take a look at the side effects of Rejuran treatment:

1. Redness and Swelling

After a Rejuran treatment, it’s common to experience some redness and swelling at the injection sites. This is a temporary side effect that typically resolves within a few hours to a day after the procedure. The swelling is often mild, but in some cases, it can be more pronounced. Cold compresses or ice packs can help reduce swelling and alleviate discomfort.

2. Bruising

Bruising is a possible side effect after Rejuran injections, especially if the injector inadvertently punctures a blood vessel. Since Rejuran is administered through multiple tiny injections, bruising might occur at the treatment sites. However, bruising is usually temporary and should fade within a week or two. Applying arnica gel or other bruise-healing creams may accelerate recovery.

3. Pain or Discomfort

While the treatment is generally well-tolerated, some individuals may experience mild discomfort or pain during the injection process. Rejuran is injected into the deeper layers of the skin, and the level of pain can vary depending on the individual’s pain tolerance. To minimize discomfort, a topical numbing cream is typically applied before the procedure.

4. Lumps or Bumps

After the injections, some patients may notice small lumps or bumps at the injection sites. These are typically the result of the gel-like substance of Rejuran settling under the skin. While these bumps usually resolve on their own within a few days, in rare cases, they may persist longer. If this happens, follow-up with the practitioner may be necessary for additional guidance.

5. Infection Risk

As with any injection-based treatment, there is a small risk of infection. To minimize this risk, it is crucial to ensure the procedure is performed by a qualified medical professional in a sterile environment. Signs of infection include increased redness, warmth, swelling, or the presence of pus at the injection site. If you suspect an infection, seek medical attention immediately.

6. Allergic Reaction

Although rare, some individuals may experience an allergic reaction to Rejuran or one of its components. Symptoms of an allergic reaction can include itching, hives, redness, and swelling beyond the typical side effects. If these symptoms occur, it’s important to contact the treating professional immediately. A patch test before treatment can help identify any potential allergies.

7. Itching and Irritation

Itching or irritation around the treated areas can occur as the skin reacts to the injections. These sensations are typically mild and go away on their own within a few days. If itching is bothersome, over-the-counter antihistamines or soothing creams recommended by your practitioner may help.

8. Skin Sensitivity

Post-treatment, the skin may become temporarily more sensitive. This means that exposure to sunlight or harsh skin care products can cause discomfort or irritation. It’s advised to avoid direct sun exposure and use gentle, non-irritating skincare products for a few days after the procedure. Wearing sunscreen regularly will also help protect the skin and prevent further irritation.

9. Temporary Skin Textural Changes

In some cases, patients may notice temporary skin textural changes, such as roughness or uneven skin tone, during the healing process. These side effects are generally short-lived and should resolve as the skin heals and regenerates.

10. Excessive Skin Dryness

Some people experience increased skin dryness after Rejuran treatment. This is because the skin may undergo a period of accelerated healing, which can cause dehydration. Keeping the skin moisturized with a hydrating serum or moisturizer will help mitigate this issue and support the healing process.

11. Delayed Healing or Inflammatory Responses

In rare instances, some individuals may experience delayed healing or inflammatory responses. This can result from an individual’s immune system reacting to the injected material. If this occurs, it’s important to consult with a medical professional who can assess the situation and recommend a course of action, such as topical steroids or anti-inflammatory treatments.

12. Over-correction or Under-correction

While uncommon, the results of Rejuran treatment may not be immediately perfect. There may be instances where the desired skin rejuvenation effects are not achieved or, conversely, where the treatment leads to over-correction in certain areas. These outcomes can usually be addressed in subsequent treatments.

Aftercare for Rejuran Treatment

After undergoing Rejuran treatment, proper aftercare is essential to maximize the benefits of the procedure and minimize the risk of side effects. Following your practitioner’s instructions closely will help ensure a smooth recovery process. Here’s a comprehensive guide on what to do and what to avoid after your Rejuran treatment:

1. Avoid Touching or Rubbing the Treated Area

One of the most important aftercare tips is to avoid touching, massaging, or rubbing the treated area for at least 24 to 48 hours. This will allow the injected polynucleotides to settle into the skin and begin stimulating collagen production without interference. Touching the skin could potentially introduce bacteria, which increases the risk of infection, so it’s crucial to keep your hands off the area.

2. Apply Cold Compresses to Reduce Swelling

If you experience any swelling or redness, applying a cold compress can help alleviate these symptoms. The cold helps to constrict blood vessels and reduce inflammation, making the healing process more comfortable. Use a clean cloth with ice or a cold pack and apply it gently to the treated area for about 10-15 minutes at a time.

3. Keep Your Skin Clean

It’s essential to keep the treated area clean to reduce the risk of infection. Use a gentle, non-alcoholic cleanser to wash your face, avoiding any harsh scrubbing or exfoliating treatments for at least a week after the procedure. Be sure to gently pat your skin dry with a clean towel, and avoid using any abrasive towels or materials that could irritate the skin.

3. Avoid Makeup for the First 24 Hours

To allow the skin to heal properly, it’s advised to avoid applying makeup for at least 24 hours after the treatment. Makeup can clog pores and introduce bacteria, which may increase the risk of breakouts or infection. After this period, if makeup is necessary, use non-comedogenic (non-pore-clogging) products and make sure to remove them gently before bedtime.

4. Use Gentle Skincare Products

For the first few days post-treatment, stick to gentle skincare products that won’t irritate your skin. Avoid products that contain alcohol, fragrances, or harsh chemicals, as these can lead to increased sensitivity. Opt for soothing moisturizers or hyaluronic acid serums to keep the skin hydrated. Your practitioner may recommend specific aftercare products tailored to your skin’s needs.

5. Avoid Sun Exposure

The treated area will be more sensitive to the sun after Rejuran treatment. To avoid potential damage, it’s crucial to limit sun exposure for at least one week following the procedure. If you must go outdoors, wear a broad-spectrum sunscreen with an SPF of 30 or higher to protect the skin from harmful UV rays. Additionally, wear a wide-brimmed hat to further shield your skin from direct sunlight.

6. Stay Hydrated

Hydration is key to supporting the healing process. Drinking plenty of water on the days following your Rejuran treatment helps keep your skin hydrated and promotes the natural healing process. This also supports your body’s ability to flush out toxins and maintain a healthy complexion.

7. Avoid Intense Physical Activity

It’s recommended to refrain from intense physical activities or exercise for at least 48 hours after your Rejuran treatment. This is because vigorous exercise increases blood flow, which may worsen swelling and bruising at the injection sites. Additionally, sweat can irritate the skin and increase the risk of infection. Opt for light activities like walking instead during the initial recovery phase.

8. Follow-up Appointments

To track your progress and ensure that you’re getting the most out of your Rejuran treatment, it’s important to attend any scheduled follow-up appointments with your practitioner. These appointments will allow your provider to assess the results and address any concerns you may have, including side effects or complications.

9. Be Patient with Results

Rejuran treatment works gradually, and the results are not immediately visible. It may take a few weeks for your skin to fully heal and for the effects of the treatment to become noticeable. Collagen stimulation and skin rejuvenation are processes that take time, so be patient as your skin naturally improves.

Who Is an Ideal Candidate for Rejuran?

Patient eligibility for Rejuran is suitable for most adults, but it is especially beneficial for:

People in their late 20s to 50s are dealing with early signs of aging
Those with dull, dehydrated, or uneven skin
Individuals suffering from acne scars or large pores
People wanting natural, non-invasive rejuvenation

However, it’s not recommended for:

Pregnant or breastfeeding individuals
Those with active skin infections or inflammatory skin conditions
People allergic to fish or salmon-derived ingredients

Frequently Asked Questions

How does Rejuran compare to dermal fillers in terms of results?

While both Rejuran and dermal fillers target facial rejuvenation, they work in fundamentally different ways. Dermal fillers focus on adding volume to specific areas of the face, like the cheeks or nasolabial folds, by injecting a substance like hyaluronic acid. In contrast, Rejuran doesn't just fill in wrinkles; it actively stimulates the skin's regenerative processes. The polynucleotides in Rejuran promote collagen production and cellular repair, improving skin texture, elasticity, and overall health over time. The result isn’t just superficial plumping, but a more natural, youthful appearance due to improved skin quality and firmness.

Is Rejuran treatment suitable for acne scars, and if so, how does it help?

Yes, Rejuran is highly effective for treating acne scars, particularly atrophic (depressed) scars. Rejuran promotes collagen synthesis and skin regeneration, which helps to fill in and smooth out the scar tissue over time. The polynucleotides encourage the body’s natural healing processes at a cellular level, addressing both the appearance and texture of the scar. Unlike treatments like microneedling or laser resurfacing that work primarily on the surface, Rejuran goes deeper by improving the skin's foundational structure, leading to more significant long-term improvement in scar appearance.

Can Rejuran be used around the eyes or on sensitive skin areas?

Absolutely! Rejuran I is specifically formulated for delicate areas like the under-eyes. This treatment is designed to address issues like dark circles, fine lines, and thin skin. The gentle yet powerful properties of polynucleotides make them ideal for sensitive regions, helping to reduce puffiness, enhance skin texture, and revive the skin’s natural radiance. Since the skin around the eyes is thinner and more delicate, Rejuran’s regenerative approach offers a non-invasive, effective solution without the need for more aggressive treatments.

How many sessions of Rejuran are typically needed for optimal results?

Most patients need about 3 to 4 sessions spaced 3–4 weeks apart to see full results. Each session works progressively to improve skin quality, starting with enhanced hydration and leading to smoother texture and reduced signs of aging. Rejuran’s effects are cumulative, so multiple sessions ensure deeper regeneration and more noticeable changes over time. After the initial treatment series, maintenance treatments every 4–6 months may be recommended to keep skin looking youthful and glowing. Many patients report that the results continue to improve for up to 6 months after their last session.

Can anyone get Rejuran treatment, or are there restrictions?

While Rejuran is safe for most adults, it's not suitable for everyone. People with active skin infections, inflammatory conditions, or allergies to fish should avoid this treatment, as Rejuran contains salmon DNA. It’s also generally not recommended for pregnant or breastfeeding women, as there’s limited research on its safety during these times. Additionally, if you have severe skin conditions or autoimmune diseases affecting skin repair, a consultation with a dermatologist is crucial. Rejuran works best for individuals with early signs of aging or skin concerns like acne scars, dullness, or uneven texture. If this sounds like your skin, Rejuran could be the perfect fit!

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